Opponents of a proposed uranium mine south of Alice Springs say the town could be polluted if the mine goes ahead.

The Alice Springs Angela-Pamela Collective is opposing the granting of an exploration licence for a site 25 kilometres south of the town.

The companies involved in the exploration say any mine would have to meet stringent environmental guidelines.

But Natalie Wasley from the protest group says people should write to the Northern Territory Government opposing the mine.

"People have until the end of May to actually make a comment to the minerals and mining Minister Chris Natt, what they think about this proposal and the minister must take note of those comments," she said.

"So we're really encouraging as many people to come along to the public meeting, get informed about the concerns and issues and then make a comment to the Minister and really have a good input into what's happening in our region."