Alice Springs native title holders have pleaded for help in opposing a proposed uranium mine south of Alice Springs.

More than 150 people attended the meeting about the proposed exploration licence for companies Cameco and Paladin to drill the Angela and Pamela uranium deposit.

Native title holder Tahnia Edwards told a public meeting at Anzac Hill High School last night that Aboriginal estate groups did not want a mine on the land.

Ms Edwards told the meeting traditional owners had no special powers to stop development on the site.

"I know from experience that if the Government has an agenda, be it development or mining, the power still sits with them.

"So we need you to stand with us in fighting this issue."

Ms Edwards told the gathering she hopes people will support the traditional owners and oppose the mine.

"I see things like this as being an opportunity for us to come together in reconciliation because, as I said before, this isn't just an issue and a burden for Aboriginal people. It's an issue and a burden for us all."

An environmental engineer has told the meeting not to believe claims companies will not mine uranium near the town unless it is environmentally safe.

Monash University lecturer Dr Gavin Mudd said companies invest millions of dollars in exploration only if they intend to mine.

"You don't spend money on a mineral deposit unless you're going to mine it, and I think it's fanciful to believe that you spend several million dollars exploring and then walk away and do nothing."

A resolution was also passed to ask Northern Territory Mines Minister Chris Natt to address another meeting in the near future.

Executives from Cameco this week met with organisers of the Finke Desert Race and the team leading the restoration of the old Ghan railway to discuss the impact a potential mine could have on them.

The Transport Hall of Fame's Liz Martin says it may jeopardise future plans for the restoration of the old railway.

"We've also got concerns with the old telegraph line that runs through threre ... But we've had some intial discussions with Cameco and we're quite happy that we'll be able to come to some sort of resolution."

Finke Desert Race president Antony Yoffa says they could move the track if mining starts.

"Each year, different sections of the 225 kilometre track are changed, so putting together a new section of track is not a huge ask."

Cameco's Jennifer Parks says there's no need for any immediate changes to the Finke Desert Race or heritage projects in the area.

"We're going to work together on what we might do in the future. I mean, it's going to be a few years before anything we do could impact on the race and whatever and we've got plenty of time to work out a solution to it."