A group of Alice Springs doctors say they will leave the town if a uranium mine goes ahead in the area.

Uranium company Cameco is exploring a uranium deposit 25 kilometres south of Alice Springs.

Sixteen doctors from the Central Australian Aboriginal Congress have written to the Northern Territory and Federal Governments threatening to immediately leave the town if the uranium mine goes ahead.

"The prompt for writing the letter was borne out of concern, out of deep concern, for the implications of having a uranium mine here, especially in terms of the loss of workforce which could be one of the consequences of having a mine here in town," said one of the signatories, Dr Koen de Decker.